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lnu.se Publications. Simple search Advanced search - Research Molecular characterization of a novel Ljungan virus (Parechovirus; Picornaviridae) reveals a fourth genotype and indicates ancestral recombination. J Gen Virol.

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Ljungan virus

The virus is a suspected human pathogen. Evidence: Literature Reference: PMID: 12163611: Authors: Johansson S, Niklasson B, Maizel J, Gorbalenya AE, Lindberg AM Title: Molecular analysis of three Ljungan virus isolates reveals a new, close-to-root lineage of the Picornaviridae with a cluster of two unrelated 2A proteins. Journal Ljungan virus cDNA. The Ljungan virus isolate 87-012 (23) was subcloned in the pCRII- TOPO vector (Life technologies, Grand Island, NY) to contain nucleotide posi-tions 301–2685 representing VP0 (VP2), VP3, and VP1(28). The resulting cDNA clone, pLV1, was verified by sequencing and used in coupled in vitro transcription translation to label Ljungan virus isolates reveals a new, close-to-root lineage of the Picornaviridae with a cluster of two unrelated 2A proteins. J Virol.

Ljungan virus

Ljungan virus (LV), which belongs to the Parechovirus genus in the Picornaviridae family, was first isolated from bank voles (Myodes glareolus) in Sweden in 1998 and proposed as a zoonotic agent. A novel picornavirus, Ljungan virus (LV), has been isolated from diabetic bank voles in Sweden. Furthermore, viral antigen and picorna viral-like particles were detected by immunohistochemistry (IHC) and electron microscopy in affected pancreatic beta cells [2, 3].
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Ljungan virus was isolated in 1999 (Niklasson et al. 1999), and has subsequently been detected in many species of small rodents, especially voles (Arvicolinae; Johansson et al. 2003; Hauffe et al. 2010; Salisbury et al. 2013).In northern Italy, this virus has been reported in a small sample of bank voles (Myodes glareolus) and yellow-necked mice (Apodemus flavicollis) with 50% and 10% Ljungan virus (LV), a picornavirus, was discovered in the Swedish vole population after six clustered deaths from myocarditis were noted in orienteers between 1989 and 1992. Four of five sera from the orienteer patients had detectable antibodies against one of the LV isolates. Wild bank voles (Myodes glareolus) develop T1D and a picornavirus, named Ljungan virus (LV), has been isolated from these animals.

Journal Ljungan virus is a picornavirus isolated from Swedish and North American rodents. Replication of Ljungan virus in cultured cells normally induces a weak and delayed cytopathic effect compared to that of many other picornaviruses. However, efficiently replicating Ljungan virus variants may evolve dur … 2021-04-01 · Ljungan virus Taxonomy ID: 172314 (for references in articles please use NCBI:txid172314) current name Det är känt att Ljunganvirus kan orsaka diabetes, hjärtmuskel-inflammation, inflammation i det centrala nervsystemet och fosterskador hos sork och mus. Utbrott av sjukdomssymptom ser ut att utlösas av höga stressnivåer, i alla fall bland gnagare. Det är fortfarande oklart om Ljunganviruset kan infektera människa.
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Ljungan virus

Ljungan Virus Replication in Cell Culture Ekström, Jens-Ola (author) Högskolan i Kalmar,Naturvetenskapliga institutionen Edman, Kjell (thesis advisor) Högskolan i Kalmar,Naturvetenskapliga institutionen Stanway, Glyn, Professor (opponent) University of Essex (creator_code:org_t) ISBN 9789189584709 Högskolan i Kalmar, 2007 English. 2009-12-01 · Ljungan virus belongs to the genus Parechovirus, family Picornaviridae. Well-known family members include poliovirus and the virus that causes foot-and-mouth disease. HPEV-1 and −2 generally cause a mild respiratory or gastrointestinal illness in children, although myocarditis and encephalitis have been reported (6) . Ljungan virus (LV) is a suspected human pathogen isolated from voles in Sweden and North America.

Full text. Free. Uppdateringen av Allärs - Allmän tesaurus på svenska och dess finska motsvarighet YSA upphörde år 2019. Resurserna för Allärs och YSA har överförts till  Ljungan virus (LV, genus Parechovirus, family Picornaviridae) is considered currently to be a rodent-borne virus. Despite suggested human disease  A pathogenic virus of the viral family which includes polio and hepatitis A was isolated from a bank vole near the Ljungan river in the mid-1990s, and named  Evidence of ljungan virus specific antibodies in humans and rodents, Finland.. Journal of Medical Virology.
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Ljunganviruset – Wikipedia

Ljungan virus is a recently identified member of the family Picornaviridae that was isolated from bank voles in Sweden. It has been shown to cause type 1 diabetes-like symptoms and myocarditis in bank voles (Myodes glareolus), and it has been suggested that it has zoonotic potential. Ljungan (Jamtlandic: Jångna or Aoa, from Old Norse *Oghn "the dreadful") is a 322 kilometer long river in Sweden.It originates near Trondheim and the Norwegian border. The river runs through the Swedish counties of Jämtland and Västernorrland. The Ljungan Virus - A Novel Pathogen The Ljungan virus was discovered in the mid-1990s.

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